I’m a bit of a science nerd. Catch me out in public, and if I’m not clacking away on a keyboard or working the day’s NYT Crossword, chances are I’ll be reading a book on neuroscience or biology or philosophy, linguistics, genetics, et cetera. I have always been drawn to examining systems to try to find the patterns and dynamics that make them the way they are, across many disciplines.
One of my favorite aspects of exploring this mosaic of sciences is how often patterns from one discipline can illuminate dynamics in others. Concepts from genetics, linguistics, and psychology frequently echo across disciplines, and some of those echoes are surprisingly relevant to how organizations grow, adapt, and sometimes falter.
I’ve worked with something like 100 small businesses over the last decade ranging from one-man operations that are nearly indistinguishable from hobbies to ballooning behemoths that are at risk of collapsing under their own weight.
Despite this range, l’ve noticed something that is perhaps not-too-surprisingly consistent: the Founder’s fingerprints are everywhere.
Whether a business is floundering or flowering, the Founder’s early choices – about how decisions get made, who gets hired, what kinds of tools are used – form a kind of organizational DNA.
Over time, that DNA can either evolve to meet new challenges, or calcify and shatter under stress. That’s what this series, The Founder Effect, is all about.
A Quick Primer on Genetics and the Founder Effect
In genetics, the Founder Effect is a phenomenon where a genetic population that begins with little genetic diversity will, over time, become even less genetically diverse. Out in the wild, this can lead to all sorts of problems: bottlenecking, culture lock-in, and even extinction. So how does this happen?
Evolution is a change in the proportion of specific genes in a gene pool over time. For example:
- A population favors brown eyes over blue
- More brown-eyed subjects reproduce than blue-eyed subjects
- The resultant population has a higher ratio of brown to blue eyes
- Repeat the cycle
(Yes, eye color is not monogenic. I promise the metaphor still holds.)
In a closed population, just a few generations of this kind of selection can eliminate blue eyes entirely.
The DNA of Business
These same issues affect businesses.
Founders often start with a small, tightly-held set of assumptions, values, and decision-making behaviors. These shape the company’s early culture, and they work for a time. As the business scales, however, they can easily become constraints, especially if the business is closed off from new perspectives.
Consider a business owner who will only hire from within their industry and their own personal network.
- The founder hires a team of like-minded individuals
- Informal norms and unspoken rules form around how things are done
- Hiring authority is distributed, but the criteria remain culturally narrow
- New perspectives are introduced, but are rarely adopted if they don’t fit
- Attempts to question norms are sidelined and reframed as ‘not how we do things’
- Difference is seen as disruption, and cultural friction increases
- Team members self-censor and conform to avoid conflict
- Repeat the Cycle
At first, this loop feels like a strength: teams are aligned, there is little friction, and high trust. Over time, it becomes a liability as the company starts to replicate without adaptation.
Before long, you have a company that is very tight-knit (great!) but ultimately resistant to change (not great). The culture becomes less diverse, less open to new ideas, and more brittle when it really matters.
In the coming posts, we’ll look at how you can identify the traces of your founding DNA and determine which genes are worth preserving, and which ones are holding you back.

